Global Alpha 1 Antitrypsin Deficiency Treatment Market Report 2023-2029

Alpha-1 antitrypsin deficiency (A1AD) is a hereditary disorder characterized by low levels of a protein called alpha-1 antitrypsin (A1AT) which is found in the blood. This deficiency may predispose an individual to several illnesses and most commonly manifests as chronic obstructive pulmonary disease (including bronchiectasis) and liver disease (especially cirrhosis and hepatoma), or more rarely, as a skin condition called panniculitis. A1AD is also more frequent among individuals with Wegener’s granulomatosis, now called polyangiitis with granulomatosis. A deficiency of A1AT allows substances that break down proteins (so-called proteolytic enzymes) to attack various tissues of the body. The attack results in destructive changes in the lungs (emphysema) and may also affect the liver and skin. Alpha-1 antitrypsin is ordinarily released by specialized, granules within a type of white blood cells (called neutrophils or polymorphonuclear leukocytes) in response to infection or inflammation. Deficiency of alpha-1 antitrypsin results in unbalanced (i.e., relatively unopposed) rapid breakdown of proteins (protease activity), especially in the supporting elastic structures of the lungs. Over years, this destruction can lead to progressive emphysema and is accelerated by smoking, some occupational exposures, and likely by other genetic modifiers of this risk which remain incompletely understood.

 

According to the new market research report “Global Alpha 1 Antitrypsin Deficiency Treatment Market Report 2023-2029”, published by QYResearch, the global Alpha 1 Antitrypsin Deficiency Treatment market size is projected to reach USD 3.68 billion by 2029, at a CAGR of 8.7% during the forecast period.

 

Figure.   Global Alpha 1 Antitrypsin Deficiency Treatment Market Size (US$ Million), 2018-2029

Based on or includes research from QYResearch: Global Alpha 1 Antitrypsin Deficiency Treatment Market Report 2023-2029.

 

Figure.   Global Alpha 1 Antitrypsin Deficiency Treatment Top 14 Players Ranking and Market Share（Based on data of 2021, Continually updated）

Based on or includes research from QYResearch: 2021 data information of Global Alpha 1 Antitrypsin Deficiency Treatment Market Report 2023-2029.

 

The global key manufacturers of Alpha 1 Antitrypsin Deficiency Treatment include Pfizer, GlaxoSmithKline, AstraZeneca, Baxter, Boehringer Ingelheim, Teva Pharmaceutical Industries, Takeda, CSL Behring, Grifols, Chiesi Pharmaceuticals, etc. In 2021, the global top five players had a share approximately 28.0% in terms of revenue.

 

 

 

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